Deflazacort in Duchenne dystrophy: Study of long-term effect
نویسندگان
چکیده
منابع مشابه
Long-term benefits of deflazacort treatment for boys with Duchenne muscular dystrophy in their second decade.
We compare the clinical course of 74 boys 10-18 years of age with Duchenne muscular dystrophy (DMD) treated (40) and not treated (34) with deflazacort. Treated boys were able to rise from supine to standing, climb stairs and walk 10 m without aids, 3-5 years longer than boys not treated. After 10 years of age, treated boys had significantly better pulmonary function than boys not treated and af...
متن کاملThe Canadian experience with long term deflazacort treatment in Duchenne muscular dystrophy
Deflazacort is the most commonly prescribed corticosteroid for the treatment of Duchenne muscular dystrophy in Canada. We review the long-term experience with deflazacort treatment at two centers in Canada; Montreal and Toronto. Deflazacort has benefitted both cohorts by prolonged ambulation, preserved cardiac and respiratory function, less scoliosis and improved survival. Common side effects i...
متن کاملComparison of Deflazacort and Prednisone in Duchenne Muscular Dystrophy
Objective Duchenne muscular dystrophy (DMD) is a degenerative disease that usually becomes clinically detectable in childhood as progressive proximal weakness. No cure is yet available for DMD, but the use of steroids improves muscle strength and function. This study has been carried out to select the best steroid for the management of DMD. Materials & Methods This study is a single-blind, rand...
متن کاملcomparison of deflazacort and prednisone in duchenne muscular dystrophy
how to cite this article: karimzadeh p, ghazavi a. comparison of deflazacort and prednisone in duchenne muscular dystrophy. iranianjournal of child neurology 2012;6(1):5-12. objective duchenne muscular dystrophy (dmd) is a degenerative disease that usually becomes clinically detectable in childhood as progressive proximal weakness. no cure is yet available for dmd, but the use of steroids impro...
متن کاملARTICLE IN PRESS Long-term benefits of deflazacort treatment for boys with Duchenne muscular dystrophy in their second decade
We compare the clinical course of 74 boys 10–18 years of age with Duchenne muscular dystrophy (DMD) treated (40) and not treated (34) with deflazacort. Treated boys were able to rise from supine to standing, climb stairs and walk 10 m without aids, 3–5 years longer than boys not treated. After 10 years of age, treated boys had significantly better pulmonary function than boys not treated and af...
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ژورنال
عنوان ژورنال: Muscle & Nerve
سال: 1994
ISSN: 0148-639X,1097-4598
DOI: 10.1002/mus.880170726